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1. General Considerations
1.1 Patients, Positioning and Coils
1.2 Sequences and Tissue Characterization
2. Primary Bone Tumors
2.1 Differentiation between Benign and Malignant Lesions
2.1.1 Morphologic and Signal Patterns
2.1.2 Post-contrast Dynamic sequences
2.2 Staging of Tumors with MR Imaging
2.2.1 Intramedullary Involvement
2.2.2 Cortical Involvement
2.2.3 Joint Involvement
2.2.4 Soft Tissue Involvement
2.2.5 Neurovascular Involvement
2.2.6 Differentiation between Extraosseous Tumor and Perineoplastic Edema
2.3 Treatment Evaluation with MR Imaging
2.3.1MR Imaging in Monitoring the Effect of Chemotherapy and Radiation
2.3.2 Diagnosis of Recurrence after Surgery, Radiation Therapy or Chemotherapy
2.4 Primary Malignant or Aggressive Bone Tumors
2.4.1 Osteosarcoma
2.4.2 Ewing's Sarcoma
2.4.3 Chondrosarcoma
2.4.4 Fibrosarcoma and Malignant Fibrous Histiocytoma
2.4.5 Angiosarcoma
2.4.6 Liposarcoma
2.4.7 Primary Lymphoma of Bone
2.4.8 Vertebral and Sacroccygeal Chordoma
2.5 Primary Benign Bone Tumors
2.5.1 Ostechondroma (Cartilaginous Exostoses)
2.5.2 Chondroblastoma
2.5.3 Enchondroma
2.5.4 Osteoid Osteoma
2.5.5 Giant Cell Tumors
2.5.6 Eosinophilic Granuloma (Histiocytosis X)
2.5.7 Aneurysmal Bone Cyst
2.5.8 Hemangioma
2.5.9 Intraosseous Lipoma
3. Metastases
3.1 Technique, Sequences and Signal Features
3.2 Differential Diagnosis of Metastatic Disease
4. Malignant Marrow Replacement or Infiltration
4.1 Signal Pattern of Normal Bone Marrow
4.2 Plasma Cell Myeloma
4.3 Lymphoma, Hodgkin's Disease or non Hodgkin's Lymphomas
4.4 Leukemia
4.5 Marrow Changes after Chemotherapy and Irradiation Therapy
4.6 Bone Marrow Transplantation

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